Journal of Bioscience and Bioengineering Vol. 100, No. 1 (2005)
Vol. 100, July 2005
Special Issue "Advanced in Biomedical Science and Engineering"
A therapeutic strategy using magnetic nanoparticles.
Tumor-specific Fab’ antibody-conjugated magnetoliposomes accumulate in the tumor tissues via the drug delivery system (DDS). Magnetite nanoparticles can be used for cancer diagnosis by magnetic resonance imaging (MRI) or for a magnetoimpedance (MI) sensor. Hyperthermia can then be induced by an alternating magnetic field (AMF) exposure. Thus, functionalized magnetite nanoparticles can offer a powerful tool for cancer therapy as well as diagnosis.
Related article: Ito, A., Shinkai, M., Honda, H., and Kobayashi, T., "Medical application of functionalized magnetic nanoparticles", J. Biosci. Bioeng., vol. 1001-11 (2005).
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